Common Upper Mammalian Brain Ontology (Cumbo)

Common Upper Mammalian Brain Ontology (cumbo)

What terms are general enough and essential to representing brains across the mammals.

The nervous system is an organ system containing predominantly neuron and glial cells. In bilaterally symmetrical organism, it is arranged in a network of tree-like structures connected to a central body.
The main functions of the nervous system are to regulate and control body functions, and to receive sensory input, process this information, and generate behavior.
- Consensus editors: Maryann Martone, Onard Mejino, Paul Katz, David Osumi-Sutherland, Mihai Bota, Jyl Boline

The central nervous system (CNS) is the part of the nervous system which includes the brain, spinal cord, and nerve cell layer of the retina.
- Consensus editors: Maryann Martone, Onard Mejino, Clif Saper, Paul Katz, David Osumi-Sutherland, Mihai Bota, Chris Mungall, Melissa Haendel, Laszlo Zaborszky, Alan Ruttenberg, Jyl Boline

The peripheral nervous system (PNS) is the part of the nervous system connected to the CNS which contains cranial nerves III - XII, spinal, peripheral and autonomic nerves.
- Consensus editors: Onard Mejino, Maryann Martone, David Osumi-Sutherland, Paul Katz, Jyl Boline

The part of the embryonic brain that gives rise to the ‘central nervous system’ of the mature brain
Synonymous with CNS
- Consensus editors: Maryann Martone, Onard Mejino, Jyl Boline

The embryonic precursor of the brain and the set of mature brain structures that derive from it
- Consensus editors: Maryann Martone, Doug Bowden, Jyl Boline

The part of the central nervous system contained within the cranium, comprising the forebrain, midbrain, hindbrain, and metencephalon. It is derived from the anterior part of the embryonic neural tube (or the encephalon). Functions include muscle control and coordination, sensory reception and integration, speech production, memory storage, and the elaboration of thought and emotions.
- Consensus editors: Adapted from NeuroLex/BIRNLex, Maryann Martone, Onard Mejino, Doug Bowden, Jyl Boline

Part of the central nervous system located in the vertebral canal continuous with and caudal to the brain; demarcated from brain by plane of foramen magnum. It is composed of an inner core of gray matter in which nerve cells predominate, and an outer layer of white matter in which myelinated nerve fibers predominate, and surrounds the central canal.
- Consensus editors: Adapted from NeuroLex/BIRNLex, Maryann Martone, Onard Mejino, Doug Bowden, Jyl Boline

A spatially aggregated collection of nerve cell bodies in the CNS, consisting of one or more subpopulations that share cell type, chemical phenotype, and connections, and including nearby cells that share the same cell type, chemical phenotype, and connections.
- Consensus editors: Clif Saper, Maryann Martone, Onard Mejino, loosely adapted from GO

A spatially aggregated collection of nerve cell bodies in the PNS, consisting of one or more subpopulations that share cell type, chemical phenotype, and connections.
- Consensus editors: Clif Saper, Maryann Martone, Onard Mejino, Chris Mungall, Melissa Haendel

Additional terms and definitions can be found here

Contents